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Nanokide TherapeuticsNanokide Therapeutics
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    Antiangiogenic therapy

    Mi-20a is a small non-coding RNA downregulated in liver sinusoidal endothelial cells during liver metastasis. Span-based nanoparticles loaded with miR-20a and decorated with chondroitin sulfate can introduce the missing miR-20a specifically in the liver sinusoidal endothelial cells blocking the angiogenic process.

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    Anti Cancer Stem Cells therapy

    Cancer Stem Cells have different protein expression profile compared with differentiated cancer cells. Identification of critical proteins related with the differentiation process is crucial. Span-based nanoparticles can be decorated with nanobodies against CSC marker CD133 to lead differentiation proteins mRNA.

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    Immunotherapy

    Computational Biology is a strong tool to find and select immunogenic epitopes. The epitope’s mRNA is included in span-based nanoparticles to lead to CSC and produce immune response

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